Latent Space: The AI Engineer Podcast
npub1ntf7j0dy6uep8u0dxl0je8jatxqj59f4srv8gt9vcujaxxga6xaqfzhv2c@drss.io
The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al. Full show notes always on https://latent.space Sponsorship and business inquiries: business@latent.space [www.latent.space](https://www.latent.space?utm_medium=podcast)
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Academia is for Ambition — Alex Zhang, MIT
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2 Oct 2026
*Last call for regular tickets for* [*AI Engineer NYC*](https://ai.engineer/nyc)*! As an exclusive for Latent Space subscribers, the first 30 of you can* [*take a 30% off
Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week
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30 Sep 2026
Three months ago Dwarkesh, who has been posting [incredible blogs and episodes](https://x.com/search?q=from%3Adwarkesh_sp%20RL&src=typed_query) about RL,
Claude Code’s Next Era — Thariq Shihipar, Anthropic
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29 Sep 2026
*We are excited to have Anthropic share their latest AI x Finance work at* [*AI Engineer New York*](https://ai.engineer/nyc/2026)*, coming up in 2 weeks!* In case you’ve been under a rock,
OpenRouter: from Seed to Stripe — with OpenRouter’s Alex Atallah & AMP’s Anjney Midha
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25 Sep 2026
From the earliest days of open-weight models to becoming the neutral routing layer for more than **10 million developers**, OpenRouter is one of the clearest bets that the future of AI will be
Runway’s WorldPrompt and the Engineering of Real-Time Worlds
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25 Sep 2026
Earlier this month, **world model** company Runway [introduced GWM Worlds 2](https://runway.com/research/introducing-gwm-worlds-2), a research preview that “turns high-fidelity video and audio
🔬Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics)
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23 Sep 2026
The OpenAI → Hugging Face attack has people asking “what else do we need to worry about?” and Anthropic’s filters flag two things: cyber-security and biology. The natural question is: what
🔬 An Oscar, Two Asteroids, and the Algorithm in Your sklearn: John Platt on AI for Science
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22 Sep 2026
How often do you get to talk to a guest who has both an Academy Award and who invented textbook machine learning algorithms? John Platt has an
Jev: System One models for Prod, not God — with Diogo Almeida, CEO, TypeSafe AI
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21 Sep 2026
*Tickets for* [*AIE NYC*](https://ai.engineer/nyc/2026) *and applications for the invite-only* [*AIE CODE*](https://ai.engineer/code/2026) *now open.* [*Join
Underwriting Superintelligence: Backing Agents you can Sue — Rune Kvist, AIUC
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16 Sep 2026
AIUC first got our attention with the NFDG backing, and have just announced a [$40M series A](https://aiuc.com/updates/series-a-announcement) today, with the most impressive industry advisor list we
Why you should work on AI for AI Research — Richard Socher of Recursive
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14 Sep 2026
From helping pioneer core ideas in NLP to now building AI systems that can automate AI research itself, [**Richard Socher**](https://x.com/RichardSocher?lang=en) **is betting that the next major step
🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing
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26 Aug 2026
A few years ago, Caltech Prof. [Anima Anandkumar](https://www.eas.caltech.edu/people/anima) set out to develop the first open-source weather model with AI. Talking to experts in the field, she was
Simulation: the new Scaling Law — Joon Sung Park, Simile AI
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21 Aug 2026
*When we first dicsussed the* [*Summer of Simulative AI*](https://www.latent.space/p/sim-ai) *in 2024 we knew it would be a brief summer, but it has recently come back with a vengeance with* [*SimGym
🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery
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11 Aug 2026
This January, four big AI × Pharma tools deals were announced at the huge JPM Pharma conference that takes over San Francisco every year.
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten
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3 Aug 2026
We first [covered Baseten](https://www.youtube.com/watch?v=KjH7Gl0_pq0) last year when DeepSeek mania was at peak hype. Now they have raised a [monster $13B
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI
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28 Jul 2026
There are roughly 100x more people who use code than who can write code. As code that “just works” becomes easier to generate, this group may be the biggest prize of all — if you can get the
Inside the Model Factory — Eiso Kant, Poolside AI
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23 Jul 2026
In recent months, the open vs closed, and [US vs China](https://www.latent.space/p/ainews-kimi-k3-28t-a50b-the-largest) discussions on model ownership and sovereign/local AI have heated up to a fever
Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
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21 Jul 2026
Bet on information If *test loss flatlines* after 1.5B parameters while *training loss continues to drop* as you scale, that tells you that your model is *limited by the amount of information* in
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
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16 Jul 2026
Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. **The next AI data center? No.** This is [Lila Sciences](https://www.lila.ai/)‘ dream for the
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
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8 Jul 2026
We’ve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from [Databricks](https://www.latent.space/p/databricks) to
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
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1 Jul 2026
This episode has a fun personal twist: There’s a counterfactual world where I was employee #1 at [Genesis Molecular AI](https://www.genesis.ml/), the company behind today’s episode. A certain
Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks
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24 Jun 2026
*We’re excited to have Databricks join us at* [*AIEWF*](https://www.ai.engineer/worldsfair/2026)*, among* [*hundreds of the top companies*](https://www.ai.engineer/worldsfair/2026#expo) *in the AI
Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan
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22 Jun 2026
[AI Engineer World’s Fair](http://ai.engineer/wf) regular bird tix will sell out ~today! [Join us next week](https://www.latent.space/p/exclusive-250-off-ai-engineer-tix) ahead of the Late Bird
The Professor of Outputmaxxing — Anjney Midha, AMP
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18 Jun 2026
*Last 4 days before regular tickets sell out at* [*AI Engineer World’s Fair*](https://www.ai.engineer/worldsfair/2026) *- this is the single biggest gathering of AI Engineers, Founders, Leaders,
🔬 The Self-Driving Lab — Joseph Krause, Radical AI
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17 Jun 2026
On the Science pod, we’ve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since our launch is [which field is
Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs
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4 Jun 2026
*The new* [*AIEWF website*](https://ai.engineer/wf) *is live! Get your tickets booked ASAP as they -will- sell out. Take the* [*AI Engineering
🔬Scaling Past Informal AI - Carina Hong, Axiom Math
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3 Jun 2026
In 2025, seven-month-old startup [Axiom solved all 12 of the problems Putnam exam](https://axiommath.ai/territory/from-seeing-why-to-checking-everything) (scoring 8/12 in the time limit) a
⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build
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3 Jun 2026
We’ve informally heard that Satya is a listener to LS for a couple years now, but it was still absolutely surreal to meet him and do a live pod at Build, together with our friends at **No Priors**,
GitHub's plan for Agents — Kyle Daigle, GitHub
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2 Jun 2026
*I’m excited to work with Microsoft once again as the presenting sponsors of the* [*AI Engineer World’s Fair*](https://www.ai.engineer/worldsfair/2026)*!* *We’ll streaming live from* [*MS
Why Video Agent models are next — Ethan He, xAI Grok Imagine
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1 Jun 2026
*We’re announcing* [*AIEWF*](https://ai.engineer/wf) *speakers this week! Take the* [*AI Engineering Survey*](https://notion.qualtrics.com/jfe/form/SV_bP07tSVMXH7ePCS)*!* Today’s guest Ethan
The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray
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28 May 2026
*The new* [*AIEWF website*](https://ai.engineer/wf) *is live!* [*CFPs*](https://ai.engineer/cfp) *close in 2 days and we will run our first New Engineer Orientation this weekend, get your tickets
🔬ESMFold2: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
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27 May 2026
*Editor’s note: In our* [*first BioHub pod with Priscilla and Mark*](http://latent.space/p/biohub) *they discussed their* [*acquisition of
🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
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27 May 2026
*Editor’s note: In our* [*first BioHub pod with Priscilla and Mark*](http://latent.space/p/biohub) *they discussed their* [*acquisition of
Giving Agents Computers — Ivan Burazin, Daytona
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21 May 2026
*Take the* [*2026 AI Engineering Survey*](https://notion.qualtrics.com/jfe/form/SV_bP07tSVMXH7ePCS) *and get >$2k in credits and* [*AIE WF tickets*](https://ai.engineer/wf)*!* On the product
Railway: The Agent-Native Cloud — Jake Cooper
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20 May 2026
*Take the* [*2026 AI Engineering Survey*](https://notion.qualtrics.com/jfe/form/SV_bP07tSVMXH7ePCS) *and get >$2k in credits and* [*AIE WF tickets*](https://ai.engineer/wf)*!* *This was recorded
The Next War Is Already Here. The West Isn't Ready. — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
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18 May 2026
The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host [**Noah
The Next War Is Already Here. The West Isn't Ready. — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
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18 May 2026
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
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18 May 2026
The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host [**Noah
AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
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14 May 2026
AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
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14 May 2026
*Special discounts up for* [*AIE Melbourne*](http://ai.engineer/melbourne) *(*[*LS discount*](http://ai.engineer/mb)*) and* [*AIE World’s Fair*](http://ai.engineer/wf) *(group discounts up to 25%
