Practical AI

6 Aug 2026

AI has moved far beyond chatbots, but what exactly are AI models, agents, agent harnesses, and multi-agent systems, and why do they matter? In this episode, Daniel and Chris break down the

30 Jul 2026

What happens when AI agents driven by a top frontier model escape their secure sandbox? Join Daniel and Chris as they unpack the AI wonk's equivalent of a murder mystery! OpenAI agents went rogue and

23 Jul 2026

The agentic transformation isn’t coming. It has already begun. Companies are deploying thousands — and sometimes tens of thousands — of AI agents. Enterprise software giants are watching their

17 Jul 2026

As AI applications become more complex, the infrastructure powering them needs to evolve. Corey Sanders, SVP of Product at CoreWeave, joins Chris to discuss why AI requires a fundamentally different

9 Jul 2026

What does it take to move AI agents from demos to reliable production systems? In this episode, Hamza Tahir explores how MLOps principles are shaping the future of generative AI, covering workflows,

2 Jul 2026

How has AI image generation evolved from blurry outputs to powerful visual intelligence models? Dustin Podell, Co-Founder and Researcher at Black Forest Labs, explains the progression from diffusion

25 Jun 2026

How do we build trust in AI agents before the AI hailstorm arrives? Emil Lassen from the Artificial Intelligence Underwriting Company (AIUC) joins the show to discuss how the enterprise flywheel of

11 Jun 2026

As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security

4 Jun 2026

AI models can win math olympiads… but still struggle to read an analog clock. In this fully connected episode, Dan and Chris break down the latest Stanford AI Index Report and explore what it

28 May 2026

What happens when AI agents start acting less like chatbots and more like coworkers? In this episode, Dan and Chris sit down with Craig McLuckie, CEO of Stacklok to explore MCP, Kubernetes, ToolHive,

21 May 2026

Open Source AI is entering a new era, one shaped by self-improving AI Agents, recursive learning systems, and rapidly evolving AI Tools that blur the line between software and autonomous

14 May 2026

U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world.  Blending political

7 May 2026

In this fully connected episode, Dan and Chris break down one of the biggest questions in AI today: do open vs. closed models still matter? From the rise of physical AI and edge devices to the

23 Apr 2026

In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible

16 Apr 2026

Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma

9 Apr 2026

In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore

2 Apr 2026

AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe

25 Mar 2026

What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at

17 Mar 2026

What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey

9 Mar 2026

AI is reshaping global power, from chip manufacturing and computing power to AI governance and US-China relations.  In this episode, Ben Buchanan, Assistant Professor at The Johns Hopkins University

18 Feb 2026

As AI accelerates innovation and adoption, leaders are facing rising cognitive load, shifting systems, and new emotional realities inside their organizations. In this episode, Deloitte’s Chief

13 Feb 2026

AI is moving fast from research to real-world deployment, and when things go wrong, the consequences are no longer hypothetical. In this episode, Sean McGregor, co-founder of the AI Verification &

2 Feb 2026

AI agents are moving from demos to real workplaces, but what actually happens when they run a company? In this episode, journalist Evan Ratliff, host of Shell Game, joins Chris to discuss his

27 Jan 2026

As AI increasingly shapes geopolitics, elections, and civic life, its impact on democracy is becoming impossible to ignore. In this episode, Daniel and Chris are joined by security expert Bruce

20 Jan 2026

As generative AI moves into production, traditional guardrails and input/output filters can prove too slow, too expensive, and/or too limited. In this episode, Alizishaan Khatri of Wrynx joins Daniel

9 Jan 2026

In this start-of-year FC episode, Chris and Daniel break down what really mattered in AI in 2025, and what to expect in 2026. They explore the rise of AI agents, the practical reality of multimodal

17 Dec 2025

As AI reshapes the workplace, employees and leaders face questions about meaningful work, automation, and human impact. In this episode, Jason Beutler, CEO of RoboSource, shares how companies can

10 Dec 2025

Chris and Daniel talk with returning guest, Ramin Mohammadi, about how those seeking to get into AI Engineer/ Data Science jobs are expected to come in a mid level engineers (not entry level). They

2 Dec 2025

Chris and Daniel unpack how AI-driven document processing has rapidly evolved well beyond traditional OCR with many technical advances that fly under the radar. They explore the progression from

26 Nov 2025

This episode is a special crossover between the Practical AI podcast and The Changelog podcast. Chris was recently invited by longtime friends Jerod Santo and Adam Stacoviak, cohosts of The

19 Nov 2025

Fireflies CEO, Krish Ramineni shares how the company is transforming AI-powered note-taking into a deeper layer of knowledge automation. He breaks down the technology behind real-time functionality

13 Nov 2025

Waymo’s VP of Research, Drago Anguelov, joins Practical AI to explore how advances in autonomy, vision models, and large-scale testing are shaping the future of driverless technology. The

10 Nov 2025

Dan and Chris unpack whether today’s surge in AI deployment across enterprise workflows, manufacturing, healthcare, and scientific research signals a lasting transformation or an overhyped bubble.

30 Oct 2025

Dan and Chris sit down (again) with Jared Zoneraich, co-founder and CEO of PromptLayer, to discuss how prompt engineering has evolved into context engineering (and while loops with tool calls). Jared

24 Oct 2025

In this fully connected episode, Daniel and Chris explore the emerging concept of tiny recursive networks introduced by Samsung AI, contrasting them with large transformer based models. They explore

16 Oct 2025

As AI systems move from simple chatbots to complex agentic workflows, new security risks emerge. In this episode, Donato Capitella unpacks how increasingly complicated architectures are making agents

9 Oct 2025

Daniel sits down with Chelsea Linder, VP of Innovation and Entrepreneurship at TechPoint, to explore the what AI innovation and impact look like on the ground.  They discuss Chelsea's journey from

29 Sep 2025

Longtime friend of the show Rajiv Shah returns to unpack lessons from a year of building retrieval-augmented generation (RAG) pipelines and reasoning models integrations. We dive into why so many AI

23 Sep 2025

In this episode, Daniel and Chris are joined by Chris Aquino, software engineer at Thunderbird to hear the story of how they developed a privacy-preserving AI executive assistant. They discuss

11 Sep 2025

In this Fully Connected episode, we dig into the recent MIT report revealing that 95% of AI pilots fail before reaching production and explore what it actually takes to succeed with AI solutions. We

27 Aug 2025

Daniel and Chris sit with Citadel AI’s Rick Kobayashi and Kenny Song and unpack AI safety and security challenges in the generative AI era. They compare Japan’s approach to AI adoption with the

19 Aug 2025

Dan and Chris break down Winning the Race: America's AI Action Plan, issued by the White House in July 2025.  Structured as three "pillars" — Accelerate AI Innovation, Build American AI

12 Aug 2025

Allegra Guinan of Lumiera helps leaders turn uncertainty about AI into confident, strategic leadership. In this conversation, she brings some actionable insights for navigating the hype and

8 Aug 2025

Dan sits down with guests Mark Daniel Ward and Katie Sanders from The Data Mine at Purdue University to explore how higher education is evolving to meet the demands of the AI-driven workforce. They

1 Aug 2025

We unpack how AI is reshaping hiring decisions, shifting job roles, and creating new expectations for professionals — from engineers to marketers. They explore the rise of AI-assisted teams, the

25 Jul 2025

In this episode, Chris sits down with Igor Nikitin, CEO and co-founder of Nice Technologies, to explore how AI and modern engineering practices are transforming the actuarial field and setting the

15 Jul 2025

In this episode of Practical AI, Chris and Daniel explore the fascinating world of agentic AI for drone and robotic swarms, which is Chris's passion and professional focus. They unpack how autonomous

7 Jul 2025

In the first episode of an "AI in the shadows" theme, Chris and Daniel explore the increasing concerning world of agentic misalignment. Starting out with a reminder about hallucinations and reasoning

2 Jul 2025

In this episode, we sit down with Joey Conway to explore NVIDIA's open source AI, from the reasoning-focused Nemotron models built on top of Llama, to the blazing-fast Parakeet speech model. We chat

27 Jun 2025

Can AI-driven autonomy reduce harm, or does it risk dehumanizing decision-making? In this “AI Hot Takes & Debates” series episode, Daniel and Chris dive deep into the ethical crossroads of AI,